Hemodynamic Shear Stress and Its Role in Atherosclerosis
 Adel M. Malek, MD, PhD; Seth L. Alper, MD, PhD; Seigo Izumo, MD


( JAMA 1999; 282:2035 - 2042 )
Figure 1. Hemodynamic Shear Stress

A, Cross-sectional schematic diagram of a blood vessel illustrating hemodynamic shear stress, taus, the frictional force per unit area acting on the inner vessel wall and on the luminal surface of the endothelium as a result of the flow of viscous blood. B,Tabular diagram illustrating the range of shear stress magnitudes encountered in veins, arteries, and in low-shear and high-shear pathologic states

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