Hemodynamic Shear Stress and Its Role in Atherosclerosis
 Adel M. Malek, MD, PhD; Seth L. Alper, MD, PhD; Seigo Izumo, MD

 
 
 

( JAMA 1999; 282:2035 - 2042 )
 

 Figure 3. Transformation of Endothelial Cell Morphology by Fluid Shear Stress
 

Bovine aortic endothelial cells exposed to physiologic shear stress (>15 dyne/cm2, left panel) for 24 hours align in the direction of blood flow while those exposed to low shear stress (right panel) do not (phase contrast; original magnification 125). See "Biological Response of the Endothelium to Shear Stress" section.

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